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KMID : 0352720080320010067
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Journal of Ginseng Research
2008 Volume.32 No. 1 p.67 ~ p.72
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Immunomodulatory Effects of Non-saponin Red Ginseng Components on Innate Immune Cells
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Sohn Eun-Hwa
Kim Ji-Hye
Choi Hye-Sook
Park Hye-Jin
Kim Byung-Oh
Rhee Dong-Kwon
Pyo Suhk-Neung
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Abstract
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for 4 h, tumoricidal activity was significantly increased. However, NSRG had effects on tumoricidal activity of macrophages at low concentration (1 ug/ml), which was not related to the production of nitric oxide. The mitogen response of lymphocytes to LPS and ConA in the spleen did not show significant differences between the control and NSRG-treated cells, whereas LPS-induced blastogenesis was slightly increased at 100 (p < 0.05). These results suggest that NSRG has differential effects on innate immune response and could be useful as immunotherapy for cancer treatment.
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KEYWORD
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non-saponin red ginseng, natural killer cells, tumoricidal activity, immunotherapy
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